Preparation Occasional sleepless nights are inevitable parts of being human. Add demanding work schedules and blue light into the mix, and relaxing can feel impossible. On these difficult evenings, you might turn to a sleep-enhancing supplement to get some shut-eye—but what are they, exactly? These treatments, often taken orally, aim to help you relax enough to fall asleep. In the United States, there are three different types, explains Dr. Abhinav Singh, facility director of the Indiana Sleep Center: melatonin formulations—available as gummies, liquids, capsules, drops, and more—that boost the natural amount of melatonin hormone produced by your brain’s pineal gland each evening; antihistamines (such as Benadryl and Tylenol PM) that can induce drowsiness, helping you fall asleep; and natural iterations, such as valerian root, GABA, chamomile, and lavender, which are known to help, but require more research....